Video
124134 Back to Transparency: Topical Losartan and the Science of Clearing Corneal Opacity
April 2026
Meeting: 2026 ASCRS Annual Meeting
Producers: Barbara Dutra, MD, PhD; Lycia Maria Sampaio, MD; Marcony Santhiago, MD, PhD; Valeria Villabona Martinez, MD; Steven Wilson, MD , ABO
Category: Refractive/Cornea Surgery
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This filme reviews the scientific rationale and clinical use of topical losartan for corneal opacity. By blocking fibrotic signaling pathways, it promotes myofibroblast apoptosis and basement membrane repair. Evidence from experimental models and human cases shows its ability to prevent and reverse stromal fibrosis, offering a new option to restore corneal clarity.