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Moderator
Seth M. Pantanelli, MD, MS, ABO
Panelists
Michelle E Akler, MD, ABO; Taj Nasser, MD, ABO
Viewing Papers
Expand a paper title to the right to view the paper abstract and authors. Use the video link to jump to that poster in the session.
Presenting Author
Morgan Micheletti, MD
Co-Authors
Michael Caplan (MD), Brian Shafer (MD), Brad Hall (PhD), Kendrick Wang (MD)
Purpose
To compare the visual outcomes and patient reported satisfaction and quality of vision of two novel intraocular lens (IOL) implantation strategies in cataract surgery patients.
Methods
This was a prospective, randomized, multicenter study of 40 post-cataract surgery patients with bilateral implantation of Panoptix IOLs or PanOptix Pro in the non-dominant eye and Vivity in the dominant eye. Patients were evaluated at 3 months postoperatively for uncorrected and distance corrected visual acuities at distance (UDVA, CDVA), intermediate (UIVA, DCIVA; 66cm), and near (UNVA, DCNVA; 40cm). Patient reported satisfaction and dysphotopsias were assessed with QUVID and IOLSAT questionnaires, and defocus curves were also measured.
Results
To date, 19 subjects in the PanOptix group and 18 subjects in the PanOptix Vivity group completed the study. In the PanOptix group, mean binocular uncorrected visual acuities at 3 months postoperatively were 0.06 ± 0.10 logMAR (UDVA), 0.07 ± 0.10 logMAR (UIVA), and 0.08 ± 0.11 logMAR (UNVA), compared to 0.04 ± 0.11 logMAR (UDVA), 0.05 ± 0.07 logMAR (UIVA), and 0.11 ± 0.07 logMAR (UNVA) in the PanOptix Vivity group. The percentage of subjects that reported experiencing starburst, halo, or glare "Never" or "Rarely" were 84%, 52%, and 37% with the PanOptix Group, compared to 72%, 72%, and 67% for the PanOptix Vivity Group, respectively.
Conclusion
The results suggest that implantation with the PanOptix and combination PanOptix Pro and Vivity IOLs can result in excellent visual acuities at distance, intermediate, and near. Both groups experienced some visual disturbances, though patient satisfaction remained high.
Presenting Author
Guy Kleinmann, MD
Co-Authors
Adi Levy (BSc, MHA), Elinor Megiddo Barnir (MD), Ehud Assia (MD), Tomer Barnea (BSc)
Purpose
To compare the visual, refractive, and patient-reported outcomes of patients implanted with two designs of trifocal intraocular lenses (IOLs): the Synergy (Johnson & Johnson, USA) and the FineVision (PhysIOL, Belgium).
Methods
Retrospective evaluation of 92 patients who underwent uneventful bilateral cataract surgery with the same trifocal IOL implantation (42 patients, 84 eyes: Synergy; 50 patients, 100 eyes: FineVision). Main outcome measures at 1 month postoperatively included uncorrected and corrected visual acuities at distance (UDVA, CDVA), intermediate VA (UIVA, CIVA), and near VA (UNVA, CNVA), Mean spherical equivalent (SE), refractive outcome, and patient-reported outcome measures (PROMs).
Results
Mean SE: Synergy +0.024±0.26D, FineVision -0.06±0.26D. UDVA and UNVA were excellent and similar (Synergy: 0.07±0.08, 0.016±0.05 logMAR; FineVision: 0.073±0.093, 0.025±0.063 logMAR, respectively; p>0.05). The Synergy had superior UIVA (0.037±0.10 vs 0.081±0.11 logMAR, respectively, p<0.01). Spectacle independence was excellent and similar for distance, intermediate, near, and whole range (Synergy: 100%, 97.4%, 94.9%,100%; FineVision: 98%, 98%, 92%, 95.8% respectively, P>0.05). The rate of significant photic phenomena was high and similar (Synergy, 53.6%; FineVision, 46.3%, p>0.05). 18.75% and 12.2% of the patients reported that it disturbed their daily life (respectively, p>0.05).
Conclusion
Both IOLs provide excellent visual outcomes, spectacle independence, and patient satisfaction. The Synergy IOL demonstrates superior uncorrected intermediate visual acuity. Both IOLs demonstrated similar high rates of photic phenomena, but with high patient tolerance.
Presenting Author
Camerynn L. Keahi, BA
Co-Authors
Carlton Yuen (MD, BSc), Caitlin Yuen (None), Brad Hall (PhD), Corban Yuen (None), Jason Tokunaga (MD), Alana Dunn (None)
Purpose
To evaluate the clinical outcomes following bilateral TECNIS Odyssey implantation in eyes with primary open angle glaucoma (POAG) targeted for plano.
Methods
This was a retrospective, single-site, single arm, observational study of visual outcomes following bilateral TECNIS Odyssey implantation in eyes with POAG. A total of 30 patients were targeted. Outcome measures included monocular and binocular uncorrected and distance corrected visual acuities at distance (UDVA, CDVA) and near (UNVA, DCNVA; 40cm), and patient self-reported spectacle independence.
Results
Data from a total of 26 patients were included. The percentage of eyes achieving 20/25 or better were 90% (47/52) for UDVA, 87% (44/52) for UNVA, and 98% (51/52) for CDVA. The percentages of eyes with ? 0.5 D of MRSE and residual astigmatism were 100% (52/52) and 100% (52/52), respectively. For self-reported spectacle independence, 8% (2/26) of subjects reported using glasses for near. In addition, 8% (2/26) of subjects reported moderate halos.
Conclusion
The results of this study suggest that patients with POAG implanted with the Odyssey IOL had good visual acuity with photopic visual acuity at distance, intermediate, and near, excellent refractive outcomes, high levels of spectacle independence, and low levels of halos.
Presenting Author
Dagny Zhu, MD
Co-Authors
Satish Modi (FRCS, MD), Jerry Hu (MD), Gregory Parkhurst (MD), Lauren Libfraind (MD)
Purpose
To evaluate visual outcomes and patient satisfaction following bilateral implantation of the Clareon PanOptix versus Tecnis Odyssey IOL in patients undergoing cataract surgery.
Methods
This was a prospective, randomized, double masked, multicenter study of post-cataract surgery patients with bilateral implantation of Clareon Panoptix or Tecnis Odyssey IOLs. A total of 246 patients (123 each group) were targeted. Patients were evaluated at 3 months postoperatively for uncorrected and distance corrected visual acuities at distance (UDVA, CDVA), intermediate (UIVA, DCIVA; 60cm), and near (UNVA, DCNVA; 40cm and 33cm). Contrast sensitivity was also measured under mesopic and photopic conditions. Patient reported satisfaction and dysphotopsias were assessed with QUVID and IOLSAT questionnaires, and defocus curves were also measured.
Results
To date, 27 subjects in the Odyssey group and 17 in the PanOptix group have completed the study. In the Odyssey group, mean binocular photopic uncorrected visual acuities at 3 months postoperatively were 0.00 ± 0.11 logMAR (UDVA), 0.11 ± 0.15 logMAR (UIVA), 0.15 ± 0.19 logMAR (UNVA 40cm), and 0.17 ± 0.15 logMAR (UNVA 33cm), compared to -0.01 ± 0.10 logMAR (UDVA), 0.03 ± 0.16 logMAR (UIVA), 0.05 ± 0.18 logMAR (UNVA 40cm), and 0.13 ± 0.16 logMAR (UNVA 33cm) in the PanOptix group. The percentage of subjects that reported experiencing starburst, halo, or glare "Never" or "Rarely" were 38%, 35%, and 62% with the Odyssey group, compared to 54%, 38%, and 63% for the PanOptix group, respectively.
Conclusion
Interim results suggest that implantation with the Odyssey and PanOptix IOLs can result in excellent visual acuities at distance, intermediate, near, and extreme near. Both groups experienced some visual disturbances.
Presenting Author
W. Andrew Maxwell, MD, PhD
Co-Authors
Kamal Das (PhD, MBA), Sebastian Marx (PhD, MSc), Vidhyapriya Sreenivasan (PhD), William Xu (PhD), Zaiwei Xu (MS)
Purpose
The Clareon PanOptix (CPO) Pro (Alcon Vision) and Tecnis Odyssey (J&J Vision) Presbyopia Correcting Intraocular Lenses (PC IOLs) are designed to provide simultaneous distance, intermediate, and near vision. This study compares the optical performance and subjective responses after monocular virtual implant of each IOL using a vision simulator.
Methods
Optical performance was compared using IOL Research bench system for the CPO Pro and Odyssey IOLs. A VirtIOL system was used to virtually implant IOL in 63 phakic, cyclopleged subjects. Pupil was fixed to 3.5mm for photopic and 4.5mm for mesopic testing. Monocular subjective blurriness ratings were collected at distance, -1.5D and -2.5D when viewing a photopic high contrast 0.2logMAR line. Subjects used an adjustable ring to indicate the perceived size of halo and starburst with each IOL while viewing an LED source in mesopic conditions. Preference for each IOL on intermediate vision quality and halo/starbursts was also collected.
Results
Data from the optical bench revealed a negligible difference in distance image contrast but CPO Pro achieved 36% higher image contrast in the intermediate-to-near vision range (-1.5D to -2.5D) as compared to Odyssey IOL. Odyssey demonstrated almost 20% higher halo intensity between 2 and 3 degrees than the CPO Pro. With virtual implant, subjective blurriness rating differences at distance and near were within 1.5 units while blurriness scores at intermediate was >2.5 units more blurry for Odyssey compared to PanOptix Pro. 89% of subjects preferred CPO Pro for intermediate vision quality. Preference around halo was 70% and starburst 89% in favor of CPO Pro.
Conclusion
The in vitro optics bench data demonstrated higher image contrast in the intermediate range and less halo for CPO Pro as compared to Odyssey. 89% of subjects reported a preference for PanOptix® Pro over Odyssey® for Simulated Intermediate Vision. 70% and ~90% of subjects preferred PanOptix® Pro over Odyssey® for Halo and Starburst, respectively.
Presenting Author
Jessica QH Choo, MBBS, FRCOphth
Co-Authors
Jodhbir Mehta (MBBS, FRCSEd, PhD), Kujani Wanniarachchi (BA), Christopher Tay (None)
Purpose
Effective lens position (ELP) is a key cause of biometry error and this is especially important during multifocal intraocular lens (IOL) implantation. Using an anterior capsule fixation IOL fixes the ELP and helps reduce biometry error. This study describes the learning curve of using an anterior capsular fixation IOL in a consecutive series.
Methods
This was a retrospective review of 100 consecutive eyes that underwent implantation with the same anterior capsular fixation IOL (Femtis IOL) by a single surgeon in a single center (Singapore National Eye Center). All patients underwent femtosecond laser-assisted cataract surgery with identical capsulotomy size. The Z8 laser was used to perform capsulotomy and fragmentation. All surgical videos were reviewed for IOL implantation time and time to fixation, as well as if there were any intra-operative complications. It was also noted if any change in surgical technique occurred during the observational period and whether this improved or worsened the surgical time and outcome.
Results
All femtosecond capsulotomies were performed successfully. 1 case of posterior capsular rupture (PCR) was noted intra-operatively. Encalvation took a mean time of 90 seconds. The first 10 cases took significantly longer than the last 10 cases. It took 15 cases for the surgeon to achieve a steady state in terms of enclavation time. In the PCR case, surgical technique was modified with a reverse optic capture style of enclavation. 4 cases had displacement of one flange following viscoelastic removal - the flange was replaced uneventfully.
Conclusion
There is a short learning curve with anterior capsular fixation IOLs. It can be overcome following 10 cases. Variations in technique allow for improved speed in implantation. It can also enable successful IOL implantation even in complex scenarios. Viscoelastic removal after IOL implantation should be done carefully to prevent flange subluxation.
Presenting Author
Byung Yi Ko, MD, PhD
Co-Authors
Seongjun Lee (MD, PhD)
Purpose
To report the short-term clinical outcomes following implantation of the continuous transitional focus intraocular lens, Precizon Presbyopic NVA� (Ophtec BV, Groningen, The Netherlands).
Methods
From October 2024 to May 2025, 23 eyes of 13 patients who received the Precizon Presbyopic NVA� intraocular lens at Nuri Eye Hospital were evaluated three months postoperatively. Measurements included monocular uncorrected distance, intermediate, and near visual acuities (expressed as logarithm of the minimal angle of resolution, logMAR), monocular and binocular defocus curves, and patient satisfaction with vision.
Results
The mean age was 64 years. At postoperative 3 months, the mean monocular uncorrected distance, intermediate, and near visual acuities (logMAR) were 0.09 ± 0.12, 0.27 ± 0.10, and 0.48 ± 0.11, respectively. In the monocular defocus curve, from +1.0 D to -1.5 D, all values were 0.19 or better; in the binocular one, the corresponding range showed 0.205 or better. Patient satisfaction scores were 6.7 for distance, 6.8 for intermediate, and 5.9 for near. The postoperative need for reading glasses was unnecessary in 41.7%, occasional in 58.3%, and never always necessary. Regarding photic phenomena, 91.7% experienced them, with glare being the most frequently reported.
Conclusion
The Precizon Presbyopic NVA� provides good distance and intermediate visual acuity, and the postoperative need for reading glasses is either occasional or unnecessary. However, patients frequently reported photic phenomena, such as glare, so caution is warranted. Further long-term studies with a larger patient population are needed.
Presenting Author
Jennifer Loh, MD
Co-Authors
Veronica Gomez (OD), Michael Venincasa (MD), Samuel Dresner (MD), William Trattler (MD)
Purpose
To evaluate the visual outcomes following cataract surgery with implantation of the PanOptix Pro trifocal intraocular lens (IOL) in a consecutive case series.
Methods
This retrospective analysis of a de-identified database included 100 consecutive eyes that underwent cataract surgery with PanOptix Pro IOL implantation at a single surgical center. Preoperative assessment comprised biometry, corneal topography, and macular optical coherence tomography (OCT). Postoperative outcomes assessed included uncorrected and best-corrected distance visual acuity (UDVA, CDVA) and uncorrected near visual acuity (UNVA). Additional parameters evaluated were refractive predictability and residual astigmatism.
Results
To date, 22 eyes have been analyzed. Uncorrected distance visual acuity (UCDVA) of 20/20 or better was achieved in 82% of eyes (18/22), and 95% (21/22) achieved 20/25 or better. All eyes (100%) were correctable to 20/20. Near visual outcomes were similarly favorable, with 91% of eyes (20/22) achieving J1+ or better and 100% (22/22) achieving J2 or better. Data collection is ongoing, with final results to be reported on 100 consecutive eyes.
Conclusion
This study will provide early clinical data regarding the visual performance of the PanOptix Pro trifocal IOL in a real-world consecutive case series. Final results are anticipated to contribute to the growing body of knowledge on advanced presbyopia-correcting IOL technologies.
Presenting Author
Magda B. Rau, MD
Purpose
To evaluate the optical, functional outcomes and patients satisfaction after Implantation of glistening free hydrophobic segmented varifocal Acunex Variomax bilateraly after Phacoemulsification.
Methods
In prospective case study from February 2020 until November 2024 we implanted after phacoemulsification through 2,4 mm incision in 80 eyes of 40 patients Acunex Variomax binocular. We evaluated the postoperative uncorrected (UCVA), best corrected visual acuity (BCVA) for distance, distance corrected intermediate and near visual acuity. The follow up was three months after implantation. The quality of vision, glare, halos and the personal satisfaction of the patients was assessed with a validated questionnaire.
Results
The mean UCVA for distance 3 months post-OP was 0,86, the BCVA 0,92. Mean DCVA for intermediate 3 months post-OP was 0,7, for near 0,79. The average glare score was 18 and halos score was 15 from maximal score of 100 for all patients, asking under mesopic light conditions
Conclusion
The new Acunex VarioMax provide excellent continuously high visual results over all distances with a high refractive predictability. The new gradual varifocal optic design with minimized transition areas seems to be a promising platform to widely avoid dysphotopic phenomena by consisting good visual performance from distance to near.
Presenting Author
Brian J Szabo, DO
Co-Authors
Nikhil Swarup (MD)
Purpose
To assess the proportion of eyes achieving premium uncorrected distance and near visual outcomes following bilateral Tecnis Odyssey intraocular lens implantation in routine cataract surgery.
Methods
Ambispective chart review of 183 eyes with complete postoperative Snellen and Jaeger acuity records at 1 and 3 months from a single refractive cataract surgery practice. Visual endpoints included uncorrected distance vision of 20/20 or better and near acuity of Jaeger 1 or higher. Secondary interventions (IOL exchange, PRK) were identified from surgical and clinical logs. Exclusion criteria included loss to follow up and incomplete visual data at visits (e.g. no near visual acuity recorded). Analysis included only bilateral cases with consistent month 1 and 3 follow-up, yielding a total cohort of 126 eyes.
Results
At month 1, 92/126 eyes (73.0%) achieved distance acuity of 20/20 or better, and 84/126 (66.7%) achieved Jaeger 1 near acuity or higher. By month 3, 97/126 (77.0%) reached 20/20 or better and 92/126 (73.0%) attained Jaeger 1 or higher. Only 1 out of 126 eyes (0.8%) required PRK for residual refractive error, and no eyes required IOL exchange. Statistical significance and further analysis in progress.
Conclusion
Among 126 consecutively operated eyes, Tecnis Odyssey IOL demonstrated outstanding premium visual outcomes with the majority attaining spectacle independence. The near-absence of secondary intervention underscores strong refractive predictability and patient satisfaction.
